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This site has got some bad ad and malware on it. I have to use stock IE at work and I see this one. Firefox and an adblocker prevent it. Not sure on Chrome.
I always use IE at work and occasionally I get a pop-up similar to the one above but it says "Only secure content displayed." I'm using a government computer so it surely has some pretty strong firewalls and spy ware. The occasional pop-up isn't that annoying.